544 Solid and hematological malignancies are not associated with increased risk for bullous pemphigoid in a national cohort of 3708 patients

Previous studies concerning the association of malignancies and bullous pemphigoid (BP) have ended up in conflicting results. Therefore, we conducted a case-control study to investigate BP. The Finnish Care Register for Health was utilized identify patients diagnosed with At least three International Classification Diseases (ICD)-10 codes L12.0 were required inclusion. Four sex age matched controls randomly selected from population register. Cancer diagnoses cases identified using ICD-10 ICD-9 diagnostic codes. Odds ratios calculated conditional logistic regression. We 3708 BP diagnosis between 1996 2019. Mean 82.3 years 57.7% them women. Any cancer found 29.3% 28.7% controls. not associated overall malignancies, solid or hematological malignancies. risk increased malignant neoplasms pharynx tonsils (Odds ratio 2.86, 95% confidence interval 1.27 - 6.43). In addition, several skin cancers (melanoma situ, carcinoma situ skin, cutaneous squamous basal cell carcinoma) Current did find overall, hematologic These results suggest that routine screening no symptoms finding suggestive is crucial. However, This may be instance due immunosuppressive medication follow-up at dermatology where physicians are familiar recognizing cancers.